Would you offer adjuvant chemotherapy in a patient with MSS colon cancer who only has residual mucin left, without viable cancer cells despite no pre-operative chemotherapy, in the colon and lymph nodes?  

This is a very specific question, and I would simplify the question to whether we should determine adjuvant chemotherapy based on the mucin seen in the lymph node for resected colon cancer. It would be very unusual that there is mucin without viable cancer cells in the colon cancer surgical specimen...