Would you offer adjuvant radiation to a patient with a vaginal spindle cell sarcoma s/p modified radical hysterectomy with bilateral sapingoopherectomy with negative margins?

Final pathology showed grade 3 spindle cell sarcoma of thee vagina involving the anterior lateral cervix 5.6cm x 4.5 x 3.4cm, <0.1cm left lateral margin. No nodal sampling was performed.

Would you consider EBRT to 45Gy + cuff brachy boost, or observe similar to a retroperitoneal sarcoma?

Answer from: Radiation Oncologist at Community Practice

What type of surgery was done? A rare disease, but with close margin at a location where the wider margin is difficult, I would favor adjuvant RT with EBRT plus brachy.

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Radiation Oncologist at Washington VAMC
The patient had an MRH and BSO with the close marg...

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Would you offer adjuvant radiation to a patient with a vaginal spindle cell sarcoma s/p modified radical hysterectomy with bilateral sapingoopherectomy with negative margins?

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