Would you offer definitive XRT for muscle invasive bladder cancer arising within a bladder diverticulum?
For patients who are not surgical candidates and have MIBC involving a moderate to large bladder diverticulum, do you consider it safe to offer concurrent chemoradiation or radiotherapy alone? Is there a risk of bladder perforation?
Answer from: Radiation Oncologist at Academic Institution
A diverticulum is a common location for bladder cancer to arise. I am not aware of any association between RT diverticula and increased risk of bladder perforation. I have personally never had an issue treating diverticula to full dose (either 64 Gy in 2 Gy fractions or 55 Gy in 20 fractions) in ter...