Would you offer gemcitabine-based chemoradiation for a resected node positive cholangiocarcinoma with negative margins that has tolerated adjuvant capecitabine?  

For resected cholangiocarcinoma, adjuvant capecitabine is considered standard of care based on the BILCAP trial (Primrose et al., PMID 30922733). This is typically administered up to 6 months following surgery. Based on intention to treat analysis median OS was 51.1 months vs 36.4 months (HR 0.81, P...