Would you offer PMRT for an axillary-only recurrence after a remote mastectomy and ALND in a patient with early stage breast cancer?

Yes. This patient's relatively early recurrence in the axilla is an indicator of either suboptimal initial surgery, aggressive biology, or both. Following axillary dissection, chemotherapy may be warranted and a discussion with the medical oncologist is certainly appropriate. Following chemotherapy,...

ABSOLUTELY, THIS PATIENT SHOULD RECEIVE RT TO CHEST WALL AND ALL DRAINING LYMPHATICS.