Would you recommend EBRT/brachythrapy for any patients with stage III- IV uterine ca in light of GOG-258 data?  

GOG-258 will certainly change management approach. The recurrence pattern between the two arms (higher distant mets in chemo RT arm and higher locoregional recurrence in chemo alone arm) suggests that sequencing of treatment may also matter. Our current approach is to have chemotherapy first and con...