Would you use abiraterone or docetaxel in addition to ADT and radiotherapy for patients with very high risk, node-negative prostate cancer?
Answer from: Medical Oncologist at Academic Institution
The most recent update from STAMPEDE's abiraterone arm in the M0 N0 very high risk setting was reported here: Attard et al., PMID 34953525 and strongly suggests that abi/ADT for 2 years plus radiation improves MFS and OS significantly and should be standard of care for men who are choosing RT in thi...
Answer from: Medical Oncologist at Academic Institution
Results from the initial STAMPEDE study and the subsequent STAMPEDE arm G included a subset of patients who fit the definition of high-risk, node negative prostate cancer. In both studies, failure free survival was improved by the addition of docetaxel and abiraterone respectively, overall survival...