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Would you use fezolinetant for hot flashes for men on ADT?
Many options for vasomotor symptoms of menopause do not work well for men on ADT. However, fezolinetant is a neurokinin B blocker, so theoretically, should be effective in this population?
Answer from: Radiation Oncologist at Community Practice
Presently, I would not use Fezolinetant. First I try Effexor. It can be helpful. But in my experience, this works in a minority of men's bothersome hot flashes.The next step, which is much more effective is low-dose estrogen patches. This has been studied in randomized clinical trials - Russell et a...
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Radiation Oncologist at Ashland Radiation Oncology, Inc.
I agree, particularly since the discounted price f...
I agree, particularly since the discounted price f...
Answer from: Radiation Oncologist at Community Practice
Start with medroxyprogesterone 20 mg daily. “Medroxyprogesterone could be considered to be the standard treatment for hot flushes in men undergoing androgen suppression for prostate cancer.”Reference: Irani et al., PMID 19963436
I have used oxybutynin with good success. It also ...
What dose of oxybutynin and frequency of dosing?
Dr. @James G. Pelton, we also have an extensive Q&...