Are there any indications to boost the axilla for women with locally advanced breast cancer who do not have clear gross residual/undissected axillary disease?
For example, a heavy burden of nodal disease with diffuse ECE? Would you treat the axilla higher than 45-50 Gy? What would you use for a boost dose?
Answer from: Radiation Oncologist at Community Practice
There is no indication for a boost in absence of undissected gross node for upfront surgery or residual node, which is not removed after neoadjuvant chemotherapy.
Comments
Radiation Oncologist at Maimonides Medical Center How high would you go for gross unresectable disea...
Radiation Oncologist at Varian Medical Systems/Allegheny health network Usually the dose is between 56 to 66 Gy, based on ...
Radiation Oncologist at Munson Medical Center What would you do in the clinical scenario of an u...
Radiation Oncologist at Varian Medical Systems/Allegheny health network Imaging negative axilla would treat involved axill...
Radiation Oncologist at Munson Medical Center Thanks for your input; distant failure is obviousl...
Answer from: Radiation Oncologist at Academic Institution
I do not boost the axilla for patients without gross disease/undissected disease. I do ensure that full coverage of the axilla is provided; when prescribing 50 Gy, I like to see 45 Gy completely encompassing the axilla, SCV and when prescribing 40.05, I like to see 38 Gy line encompassing.
In...
Comments
Radiation Oncologist at Maimonides Medical Center How high would you go for gross unresectable disea...
Radiation Oncologist at Cleveland Clinic For gross unresectable disease, I have used 66 Gy,...
Radiation Oncologist at Munson Medical Center I'll pose the same question...What would you do in...
Radiation Oncologist at Cleveland Clinic These are tough cases, and I have seen these mostl...
Radiation Oncologist at Munson Medical Center Exactly what I’ve noticed as well. Most have...
Radiation Oncologist at Vice Chair, Northside Hospital Cancer Institute Is there any experience for adding concurrent xelo...
Radiation Oncologist at Cleveland Clinic I have done this in the past, toxicity is a concer...
Answer from: Radiation Oncologist at Community Practice
If no gross/undissected disease, I try to ensure 90-95% coverage depending on risk profile. If gross disease, I attempt to escalate to 66 Gy and consider concurrent therapy in the context of MDTB. Usually xeloda per MDA phase 2 study, but have used other radiosensitizers based on medical oncolo...
How high would you go for gross unresectable disea...
Usually the dose is between 56 to 66 Gy, based on ...
What would you do in the clinical scenario of an u...
Imaging negative axilla would treat involved axill...
Thanks for your input; distant failure is obviousl...