Questions discussed in this category
Family history is notable for CVA and early onset MI in nonsmokers, but no personal or family history of VTE. APLS testing is negative. Previously fou...
It seems clear that longer monitoring yields more AF detected. What is less clear to me is whether all ILR-detected AF is relevant and merits anticoag...
Would you recommend left atrial appendage occlusion with or without continuing anticoagulation? In light of Maarse et al., JAMA Neurology 2024.
How would you adjust statin therapy in these patients?
In light of a publication by Sakusic et al., PMID 39102615 suggests an increased risk of ICH expansion in patients with heparin bridge compared to sta...
How do you balance between having a higher long-term blood pressure to prevent flow failure and leading to worsening of stenosis or occlusion from the...
Individual times in the therapeutic range while on VKA treatment was not registered in FRAIL-AF.
In FRAIL-AF, switching VKA therapy to a NOAC was associated with higher risk of bleeding in elderly, frail patients.
In FRAIL-AF, participants were switched from VKA to dabigatran, rivaroxaban, apixaban, and edoxaban.
Do you distinguish between primary and secondary prevention? Wilson et al., PMID 31130428 is helpful, but curious how people apply this data in practi...
How do you approach secondary stroke prevention for patients with ischemic stroke, atrial fibrillation, and signs of cerebral amyloid angiopathy/micro...
How does presence of intraventricular hemorrhage change your recommendations?
For a relatively young, medically compliant patient with HFrEF (EF<35%) and h/o embolic stroke, what is the consensus of starting AC for secondary ...
For example, with a Watchman device? What is the evidence behind this?
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Papers discussed in this category
Stroke, 2020 Aug 06
Ann Neurol, 2020 Aug 05
J Am Coll Cardiol,
The New England journal of medicine, 2012-05-17
The New England journal of medicine, 2018-10-04
The New England journal of medicine, 2019-05-16
Heart, 2019 Apr 08
American heart journal, 2010-07
Lancet, 2021 Aug 27
The New England journal of medicine, 2013-03-21
Neurology, 2013-08-13
The New England journal of medicine, 2017-09-14
Circ Cardiovasc Interv, 2022 Jun 23
JAMA, 2021 Dec 14
JAMA Neurol, 2020 Jul 01
JAMA Neurol, 2022 Nov 01
Stroke, 2021 May 24
JAMA neurology, 2019-04-01
Lancet Neurol, 2019 May 23
JAMA Neurol,
Lancet Neurol, 2018 Jan 10
Circulation, 2023 Aug 27
American heart journal, 2017 Apr 24
The New England journal of medicine, 2023 Aug 25
Stroke, 2007-12
The New England journal of medicine, 2006 Aug 10
European heart journal, 2020 Jan 01
Journal of the American Heart Association, 2023 Sep 08
Neurology, 2024 Aug 05
Neurology, 2024 Aug 05