Neurology

Sarcoidosis

Questions discussed in this category

Do you send CSF or serum ACE levels in the workup of neurosarcoidosis?

If not, are there any serum or CSF tests you consider to be helpful?

3 Answers available

How do you workup patients with neuropathy suspected to be secondary to sarcoid?

Is a biopsy or EMG helpful in confirming the etiology? What is the best treatment for sarcoid neuropathy?

1 Answer available

How do you dose steroids in neurosarcoidosis patients with a worsening clinical symptoms or MRI findings?

Do you treat with only an IV steroid pulse or do you use an oral steroid taper as well? How long of a taper do you typically use?

1 Answer available

In a patient with neurosarcoidosis who required infliximab for initially refractory symptoms but is now stable, how do you decide on the optimal time to de-escalate therapy?

1 Answer available

What steroid-sparing agent would you use for treatment of neurosarcoidosis with leptomeningeal and parenchymal involvement?

1 Answer available

Papers discussed in this category

Neurology, 2016 Nov 16

Treatment of neurosarcoidosis: A comparative study of methotrexate and mycophenolate mofetil.

Clin. Chest Med., 2015 Sep 26

Neurosarcoidosis.

Clin. Exp. Rheumatol., 2013 Dec 09

Anti-TNF-α therapy in the management of severe neurosarcoidosis: a report of five cases from a single centre and literature review.

Neurology, 2017-11-14

Infliximab for the treatment of CNS sarcoidosis: A multi-institutional series.

Neurol Neuroimmunol Neuroinflamm, 2020 Jul 27

Infliximab treatment in pathology-confirmed neurosarcoidosis.

JAMA neurology, 2018-12-01

Definition and Consensus Diagnostic Criteria for Neurosarcoidosis: From the Neurosarcoidosis Consortium Consensus Group.

Journal of neuroimmunology, 2022 Apr 09

Peripheral neuropathy in sarcoidosis.

Neurology(R) neuroimmunology & neuroinflammation, 2021 Oct 04

Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment.

Lung, 2015 Nov 13

Diagnostic Utility of Angiotensin-Converting Enzyme in Sarcoidosis: A Population-Based Study.

Biomolecules, 2022 Sep 30

Performance of Serum Angiotensin-Converting Enzyme in Diagnosing Sarcoidosis and Predicting the Active Status of Sarcoidosis: A Meta-Analysis.

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