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Autoinflammatory disorders   

Questions discussed in this category

Which other agent would you consider for a patient with VEXAS who has failed methotrexate, multiple TNF inhibitors, Tocilizumab, and Ruxolitinib?
1 Answer available
Do you recommend genetic screening for FMF in asymptomatic first-degree relatives with a strong family history (multiple family members, severe/refractory disease)?
1 Answer available
How do you utilize cytokine panels in your clinical practice?
Is there utility when classic inflammatory markers (ESR,CRP) or disease specific markers (C3, C4, dsDNA) do not correlate with patients disease activi...
1 Answer available
What is your approach to evaluation and management of a patient with Blau Syndrome and GI manifestations?
2 Answers available
How do you approach management of Adult Onset Still's disease in a patient with ongoing fatigue and inflammatory joint pain despite methotrexate, colchicine, canakinumab and tocilizumab?
Heritable autoinflammatory gene testing negative. Is there a role for TNF inhibitor?
3 Answers available
How do you decide when to obtain genetic testing for suspected autoinflammatory conditions in adults?
2 Answers available
How do you approach management of a patient with persistent EBV infection and MAS despite treatment with Rituximab, anakinra and canakinumab? 
Would you consider alternative B cell depleting therapies such as ofatumumab or ocrelizumab?
1 Answer available
Do you recommend using IL-1/IL-6 inhibitors in COVID-19 multisystem inflammatory syndrome in adults (MIS-A)?
1 Answer available
Do you routinely obtain bone marrow biopsy in newly diagnosed autoimmune hemolytic anemia when working up potential underlying etiologies?
1 Answer available


Papers discussed in this category

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2022 Oct 17
VEXAS Syndrome-A Review of Pathophysiology, Presentation, and Prognosis.

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