Questions discussed in this category
Family history is notable for CVA and early onset MI in nonsmokers, but no personal or family history of VTE. APLS testing is negative. Previously fou...
Labs with normal PT, but prolonged PTT (47 sec, ULN 40 sec) that does not correct on immediate mix. Lupus anticoagulant negative (DRVVT and hexagonal ...
Thrombophilia testing, including JAK2 is negative. When would you stop anticoagulation?
When do you determine SSRI therapy is unsafe to pursue in such situations?
Should some patients get 325 mg instead of 81mg at least for a certain amount of time, such as patients in the acute phase of ischemic stroke or patie...
Considering the short half-life, at what point would it be deemed too late to administer any reversal agent, and to consider withholding it?
In light of ANNEXA-I RCT results: Connolly et al., PMID 38749032.
Are there specific mass features that would influence your treatment decision?
When would you consider using anticoagulation and for how long?
Is there any evidence supporting the use of heparin boluses?
The ASH 2020 guidelines have "recommended that adults with HbSS or HbSβ0 thalassemia be screened at least once for silent cerebral infarcts even ...
In FRAIL-AF, switching VKA therapy to a NOAC was associated with higher risk of bleeding in elderly, frail patients.
In FRAIL-AF, participants were switched from VKA to dabigatran, rivaroxaban, apixaban, and edoxaban.
Also how would you manage this perioperatively?
The patient has no known history of autoimmune disease.
Do we prophylactically place patients on anticoagulation after one episode?
Besides MRI/MRV brain, are there other diagnostic imaging that should b...
In the setting of no personal or family history and no other risk factors for thrombosis, is systemic anticoagulation warranted if local treatments (e...
How do you approach secondary stroke prevention for patients with ischemic stroke, atrial fibrillation, and signs of cerebral amyloid angiopathy/micro...
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Papers discussed in this category
American journal of hematology, 2023 May 12
The New England journal of medicine, 2014 Aug 21
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2019-08
Stroke, 2021 Sep 14
Stroke, 2015-03
BMJ open, 2014-12-02
J Am Heart Assoc, 2020 Nov 23
Am J Hematol,
Cancer causes & control : CCC, 2010-03
Atherosclerosis, 2001-06
The American journal of clinical nutrition, 2008-10
Circulation. Cardiovascular genetics, 2008-12
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012-01
Human genetics, 2012-05
PeerJ, 2013
Nature, 2016-08-18
Am J Hum Genet, 1998 May
Am J Reprod Immunol, 2011 Jan 18
Am J Reprod Immunol, 2012 Aug 06
BMC Cancer, 2008 Nov 07
BMJ Case Rep, 2012 Nov 15
BMJ Case Rep, 2013 Jun 13
Mol Biol Rep, 2010 Jun 08
Mol Biol Rep, 2010 Nov 16
Nat Genet, 2008 Jul
Proc Natl Acad Sci U S A, 2001 Mar 13
Mol Biol Rep, 2018 Mar 29
Transfus Apher Sci, 2014 Jan 08
J Matern Fetal Neonatal Med, 2015 Jul 02
Clin Neurol Neurosurg, 2013 Mar 21
J Hum Genet, 2006 Feb 18
Arthritis and rheumatism, 2007-07
Stroke, 2014-07
Cochrane Database Syst Rev, 2020 Oct 12
Archives of internal medicine, 1997-10-13
Lupus, 2011-02
Annals of the rheumatic diseases, 2019-10
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Lupus,
Stroke, 2021 May 24
J Autoimmun, 2018 Feb 13
Int J Med Sci, 2009 Dec 05
Blood Adv,
The New England journal of medicine, 2018-02-15
N Engl J Med, 2020 Mar 29
N Engl J Med, 2003 Jul 10
JAMA neurology, 2020 Aug 01
Stroke, 2023 Sep 07
J Clin Med, 2020 Mar 10
Hematology Am Soc Hematol Educ Program, 2021 Dec 10
JAMA Neurol, 2019 Dec 01
Circulation, 2023 Aug 27
Lancet Neurol, 2019 May 23
The Lancet. Neurology, 2021 Mar 17
Pharmacological research, 2016 Aug 10
The Annals of pharmacotherapy, 2018 Aug 06
The New England journal of medicine, 2024 May 16
Stroke, 2024 Jan 29