Questions discussed in this category
Cholesterol Treatment Trialists' (CTT) Collaboration
The REPRIEVE trial included participants who were between 40 and 75 years old.
(Since there is some suggestion that stains convert vulnerable plaque to stable calcified plaque and increase calcium score)
If so, is there a quantitative calcium score or a reported severity of CT coronary artery calcification that would lead you to start daily aspirin?
And when would you consider referral for staged/complex PCI instead?
Sabatine et al., PMID 28304224
If these patients were already prescribed non-selective beta blockers outpatient, do you recommend withholding these medications in the acute phase?&n...
Would you extend length of time for anticoagulation if the apex remained akinetic on surveillance TTEs?
If LHC is deferred, would you consider loading with plavix and treating for ACS for 48 hours (assuming acceptable bleeding risk) and optimizing GDMT p...
Would you consider further imaging like coronary calcium scoring or coronary CTA to further risk stratify them?
How would you assess response to bempedoic acid and its safety on outpatient labs, and how frequently would you have labs monitored?
How often should cardiac MRI be ordered in this context?
Are there any significant benefits to lowering moderately elevated lipoprotein A levels?
If so, would you prefer a P2Y12i over low-dose aspirin?
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Papers discussed in this category
J Am Coll Cardiol, 2019 Jan 28
Stroke, 2019-06
Journal of cardiovascular imaging, 2018 Jun 22
J Am Coll Cardiol, 2020 Sep 29
Clinical medicine & research, 2013-12
N Engl J Med, 2017 Mar 17
Lancet (London, England), 2015 Jul 15
The New England journal of medicine, 2020 Mar 30
Circulation. Cardiovascular quality and outcomes, 2020 Mar 10
JAMA cardiology, 2021 Feb 01
The New England journal of medicine, 2001-08-16
Lancet (London, England), 2023 Mar 06
Circulation, 2023 Nov 13
Circulation, 2023 Nov 11
Circulation. Cardiovascular quality and outcomes, 2023 Nov 06
American heart journal, 2017 Apr 24
The New England journal of medicine, 2023 Nov 11
American heart journal, 2023 Mar 25
JAMA, 2023 Nov 11
The British journal of cardiology, 2022 Jul 19
Journal of clinical lipidology, 2020 Jan 02
Clinical cardiology, 2020 Feb 19
PloS one, 2023 Nov 16
Curr Rheumatol Rep, 2020 Aug 26
American heart journal, 2020 Oct 13
The New England journal of medicine, 2024 Apr 07
Circulation, 2016-12-13
American heart journal, 2022 May 17
The New England journal of medicine, 2024 Apr 06
JACC. Cardiovascular interventions, 2014-07
The New England journal of medicine, 2010 Sep 22
JACC. Cardiovascular interventions, 2020 Feb 12
Circulation research, 2020 Jun 18
Journal of the American College of Cardiology, 2024 Aug 29