Rheumatology

Psoriatic arthritis   

Questions discussed in this category



How do you view it relative to existing options like TNFi, IL-23, or IL-17s like ixekizumab?

For example, in patients with many swollen/tender joints, enthesitis, nail involvement do you expect particularly good response? Are there patients in...

How will you counsel patients about the risk and what strategies will you use to mitigate the increased risk of fungal infections see in the BE COMPLE...

The patient has ongoing inflammatory arthritis despite methotrexate, apremilast, and jak inhibitor trials.

Given the drug-drug interaction, do you monitor more closely for methotrexate toxicity, counsel on symptoms of methotrexate toxicity, or avoid the com...

What side effects do you highlight in conversation with them? How do you approach toxicity monitoring?

Assuming no symptoms of TB, should patients be treated for latent TB prior to starting TNF inhibitors or other immunosuppressive agents?

In contrast to TNF inhibitors for psoriatic arthritis, which seem to peak and maintain response percentages, the DISCOVER-2 Trial (McInnes et al., PMI...

In clinical practice continued steroid dependence is often seen as a reason to switch therapy and providers can be especially hesitant to use systemic...

Based on the results of the DISCOVER-2 Trial (McInnes et al., PMID 34719872), should guselkumab be used prior to anti-TNF therapy in these patients?


Papers discussed in this category


Arthritis Rheumatol, 2019 Jan

Ann. Rheum. Dis., 2019 Sep 28

Lancet,

Arthritis & rheumatology (Hoboken, N.J.), 2016-05

Arthritis Rheumatol, 2019 Oct

Rheumatology (Oxford),

Rheumatology (Oxford),

Clin. Exp. Rheumatol., 2016 Dec 13

Lancet, 2015 Oct 01

J Rheumatol Suppl,

Nat Rev Rheumatol,

Rheumatology (Oxford),

Ann Rheum Dis, 2015 Dec 07

J Med Imaging Radiat Oncol,

J Ultrason, 2016 Mar 29

Annals of the rheumatic diseases, 2017-04

Arthritis Care Res (Hoboken), 2018 Aug

Arthritis Care Res (Hoboken),

Journal of clinical medicine, 2022 Apr 21

Clinical and experimental rheumatology, 2020 Feb 11

Journal of clinical medicine, 2021 Dec 29

Clinical and experimental rheumatology, 2022 Mar 01

Curr Med Chem,

Pathology, 2017 Mar 11

Arthritis Care Res (Hoboken), 2019 Jan

Arthritis Rheumatol, 2022 Feb 07

Annals of internal medicine, 2018-01-16

J Immunother Cancer,

Rheumatology (Oxford), 2014 Sep 16

The Journal of rheumatology, 2012-01

JAAD Case Rep, 2019 Oct 10

Clinical rheumatology, 1988 Sep

Journal of the American Academy of Dermatology, 1987 Apr

Journal of the American Academy of Dermatology, 2020 May 19

Annals of the rheumatic diseases, 2018-09

Arthritis & rheumatology (Hoboken, N.J.), 2019-02

RMD open, 2020 Feb

The New England journal of medicine, 2014 Jun 05

Trials, 2022 Sep 05

Annals of the rheumatic diseases, 2024 Mar 18

Ann Rheum Dis, 2020 Dec 17

The Journal of rheumatology, 1997 May

British journal of rheumatology, 1995 May

Expert review of anticancer therapy, 2009-01

Lancet Gastroenterol Hepatol, 2023 Feb 01