Do add a macrolide for immunomodulatory effect in patients with macrolide-resistant M. abscessus?  

I think using azithromycin is something that definitely can be considered, but on an individual basis; if there is significant bronchiectasis with exacerbations, then it makes sense to consider azithromycin; more likely to consider also if there are other microorganisms, especially Pseudomonas drivi...