Please select the option that best describes you:
Topics:
Breast Cancer • Radiation Oncology
Do you consider dermal invasion an indication for PMRT in the absence of other risk factors?
If a patient has early stage disease with peau d'orange but does not meet criteria for inflammatory breast cancer, is PMRT indicated?
Answer from: Radiation Oncologist at Academic Institution
Did the patient have neoadjuvant chemotherapy between diagnosis and surgery?
If yes, than I would treat based on upfront clinical staging. If over 60 and no reconstruction would consider 40 Gy/15 fx to chest wall and nodes otherwise 50/25 fx or Alliance Trial if interested.
If no n...
Sign in or Register to read more
Answer from: Radiation Oncologist at Community Practice
The limited data on non inflammatory breast ca with dermal lymphatic invasion suggest higher locoregional recurrence and I do offer PMRT
Answer from: Radiation Oncologist at Academic Institution
I wonder whether dermal lymphatic invasion is considered the same thing as invasion of the dermis? Based on the clinical description of peau d'orange, dermal invasion for this particular case may suggest tumor involvement of the dermal lymphatics which can be missed or difficult to identify on...
Answer from: Radiation Oncologist at Academic Institution
There is dermal lymphatic invasion and dermal lymphatic invasion. Do we treat patients with limited lymphovascular invasion and negative nodes if there are no other indicators? Probably not, based on subset analyses from multiple studies. However, refer to a recent Red Journal arti...