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Do you offer adjuvant radiation therapy for sacral chordoma s/p gross total resection with close margins <0.5 cm?

What dose would you use? For negative margins do you offer 50-50.4 Gy/25-28 fractions? What target volume margins do you typically recommend on the post-operative bed?

Answer from: Radiation Oncologist at Academic Institution

Yes to adjuvant RT, but doses of 50-60 Gy have no benefit in chordoma. 70 Gy is required even with R0 margins. See Konieczkowski et al., PMID 32147017 for a full discussion of the literature.

Comments

Radiation Oncologist at Munson Medical Center
@David Konieczkowski. What an excellent article, t...

Radiation Oncologist at Massachusetts General Hospital
Agree with Dr. @David Konieczkowski with the addit...

Radiation Oncologist at Ohio State University James Cancer Center
Many thanks and warmly agreed, @Thomas F. DeLaney....

Radiation Oncologist at Mount Sinai Hospital
Agree with Dr. @Forster's glowing review. Very inf...

Please select the option that best describes you:

Do you offer adjuvant radiation therapy for sacral chordoma s/p gross total resection with close margins <0.5 cm?

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