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Topics:
Gastrointestinal Cancers • Medical Oncology
Do you offer neoadjuvant FOLFOX for elderly patients with locally advanced rectal cancer receiving short course radiation?
If an older patient is only fit enough for single agent fluoropyrimidine therapy, would you prefer to give this neoadjuvantly or adjuvantly?
Answer from: Radiation Oncologist at Community Practice
I would approach this case somewhat analogously to the bulk of cases of locally advanced rectal cancer by first getting an understanding of the patient's physiologic age/functional status, surgeon’s opinion on operability and concern for margins, and imaging-defined risk factors- location of t...
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