Do you routinely prescribe an anticholinergic agent for EPS prophylaxis when starting or continuing antipsychotics, or do you prefer to use it only as needed (prn) if/when symptoms develop?  

EPS from an antipsychotic occurs early in the course of treatment or with dose escalation. EPS is usually transient so anticholinergics should not be used long-term. Also, anticholinergics have a lousy side effect profile. Ideally, we treat patients with drugs that don't have side effects that requi...