Do you screen for HLA-B*5801 prior to starting allopurinol in patients of backgrounds other than Asian or African-American?

Specifically in patients of Vietnamese background? An association has been shown between HLA-B*5801 and the risk of allopurinol hypersensitivity reactions particularly in patients of Han Chinese, Korean, and Thai descent, but less information is available for other groups.

Answer from: at Academic Institution

The guidelines now recommend checking for the presence of the HLA-B*5801 gene only in Asians and African-Americans. However, in our clinic, we are checking for the presence of this gene on everybody who becomes a candidate to receive allopurinol, partly due to the fact that we are doing a study. Int...

Comments

at Premier Medical Associates
Any cost-benefit analysis?

at Harvard Medical School
I would wonder about how costly “universal s...

at UTMB Health
Well, if a Caucasian patient who is not supposed t...

Please select the option that best describes you:

Do you screen for HLA-B*5801 prior to starting allopurinol in patients of backgrounds other than Asian or African-American?

Related Questions