Do you still consider changing atypical antipsychotics that are working well in children undergoing puberty if the prolactin levels are high but there are no symptoms of drug-induced hyperprolactinemia?
Is there a prolactin level in asymptomatic children when you should consider switching to alternative atypical antipsychotics?
Answer from: at Community Practice
I consider the risk of osteoporosis if I believe it may be used long-term, even if asymptomatic. Typically, I warn parents of the risk but continue the medication if the prolactin is only mildly elevated. I find it rare to find an adult patient who is taking the same drugs they did in adolescence. L...
For drug-induced hyperprolactinemia, first, I typically want to make sure that it is the antipsychotic causing it. Generally, if so, the elevation is mild (two digits, mean 50s) and, if asymptomatic (which is more common), I monitor and educate the parent/child on the long-term possible effects of h...
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at Thapar Renu K Office One needs to be vigilant before make patients actu...
I would not switch medication if prolactin is only mildly elevated and that patient is doing quite well with current treatment. I would advise be alert to the possibility that certain medications can cause delayed onset of puberty, which can be an insidious adverse effect, since puberty onset occurs...