Do you use oral fosfomycin as a treatment option for uncomplicated cystitis due to ESBL producing E coli?  

Fosfomycin is one of the first-line drugs for uncomplicated UTI listed in the Infectious Diseases Society of America (IDSA) UTI treatment guidelines (these guidelines are currently being updated).  It is the only single-dose drug approved for UTI and is an effective option.  It does have a...