Does the presence of DCIS in conjunction with invasive breast cancer require consideration of adjuvant RT where invasive disease alone may allow for omission?

Were patients with mixed histology included in the omission trials?

Answer from: Radiation Oncologist at Academic Institution

I'm not sure there is a lot of data in the PRIME II/CALGB 9343 subset of patients looking at impact of associated DCIS in conjunction with invasive disease and its impact on recurrence with and without radiation therapy. I have not considered this an additional risk factor and have offered omis...

Comments

Radiation Oncologist at University of Louisville
Would your recommendation change if the DCIS was l...

Radiation Oncologist at Cleveland Clinic
If DCIS is large 2.5 cm and high grade, was the ov...

Radiation Oncologist at Indiana University Health
@Chirag S. Shah, if a >50yo patient has G3 DCIS...

Radiation Oncologist at Cleveland Clinic
Definitely an evolving area. That being said, if t...

Answer from: Radiation Oncologist at Community Practice

In most cases of invasive disease, if you look, you will find some DCIS and thus the presence of DCIS with invasive disease would not change my management.

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Does the presence of DCIS in conjunction with invasive breast cancer require consideration of adjuvant RT where invasive disease alone may allow for omission?

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