Have you adopted the use of low dose morphine for treatment of cough in patients with IPF?

If so, what dose and formulation of morphine do you prefer?

The PACIFY COUGH trial utilized controlled-release morphine 5 mg BID, however the lowest dose tablet size available is 15 mg.

Answer from: at Community Practice

Yes, I selectively use low-dose morphine for the treatment of chronic cough (lasting more than 8 weeks) in certain patients with idiopathic pulmonary fibrosis (IPF).This includes individuals who demonstrate somewhat preserved lung function (specifically, a forced vital capacity [FVC] of 45% or more ...

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at Mass General Brigham Pentucket Medical
Any data on use of amitriptyline in these patients...

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Have you adopted the use of low dose morphine for treatment of cough in patients with IPF?

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