How do you approach a patient with Paget’s disease of bone with elevated alkaline phosphatase and history of chronic kidney disease?

Patient with a history of CKD stage 4. Alkaline phosphatase 4x upper limit of normal.

Answer from: at Academic Institution

Tough one. I might try low-dose risedronate and monitor the calcium and creatinine values often.

Comments

at Bay Area Arthritis and Osteoporosis
Thank you, Dr. @Lane!