How do you approach treatment for metastatic cutaneous squamous cell carcinoma after standard chemotherapy failure?
Is the use of immunotherapy being considered, and if so, is the data extrapolated from treatment of mNSCLC and head and neck SCC?
Answer from: Medical Oncologist at Academic Institution
Immunotherapy seems to be active in cutaneous squamous cell carcinoma and I think checkpoint inhibitors are a good option for patients who have failed cytotoxic chemotherapy or cannot receive chemo. In an expansion cohort of a phase I study of REGN2810, a PD-1 inhibitor, the response rate in 2...