How do you approach treatment of a locally advanced primary tongue SCC lesion spanning oral cavity and base of tongue?
In the case where patient history and pathology markers are uninformative to distinguish oral cavity vs oropharynx, do you tend to favor up front surgery or definitive CRT?
Answer from: Radiation Oncologist at Academic Institution
I classify site based on bulk of disease. ChemoRT for tongue base and surgery and postop RT for oral tongue. If it’s too extensive to distinguish, which is infrequent, chemoRT, particularly if total glossectomy would be required.