How do you manage local recurrence of a resected stage III BRAF WT melanoma occurring during or shortly after completion of adjuvant nivolumab?
Would you offer nodal dissection and/or additional adjuvant immunotherapy in addition to wide local excision?
Answer from: Medical Oncologist at Community Practice
Data presented at ASCO 2019 by Carina Owen suggests that with resection alone in this setting, roughly 50-60 percent of patients will develop recurrent disease. Therefore, resection alone is likely insufficient for these patients. If resection of the local recurrence is pursed, neoadjuvant or altern...