How would you approach consolidative rectal irradiation for a patient with liver-confined metastatic rectal adenocarcinoma, who has sustained a near-CR after CAPEOX, capecitabine, and ongoing bevacizumab?

The patient has sustained a positive response for >1 year after diagnosis.

Answer from: Radiation Oncologist at Academic Institution

Yes, they are curable with liver directed therapy, I would treat with curative intent non-operative management. If they are not curable, would not treat unless until progression.

Comments

Radiation Oncologist at Mon Health
Thanks. What is your standard dose/fractionation a...

Radiation Oncologist at Torrance Memorial Medical Center
@Christopher H. Crane, how would you deal with the...

Radiation Oncologist at Memorial Sloan-Kettering Cancer Center
The half life of Avastin is around three weeks. Ho...

Radiation Oncologist at Torrance Memorial Medical Center
Thank you! That’s very helpful.

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How would you approach consolidative rectal irradiation for a patient with liver-confined metastatic rectal adenocarcinoma, who has sustained a near-CR after CAPEOX, capecitabine, and ongoing bevacizumab?

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