How would you manage papillary variant squamous cell carcinoma of the oropharynx?
Does papillary histology influence your decisions regarding surgery, chemo, radiation dose or nodal coverage?
Answer from: Radiation Oncologist at Academic Institution
We prefer to approach papillary variant squamous cell carcinoma with a surgical approach. These cancers can be related to HPV (either high risk or mucosal subtypes) and generally carry a good prognosis. A selected neck dissection should be considered and if the tumor is larger or more invasive than ...