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Is it ever appropriate to reduce urate lowering therapy dose due to very low urate levels?
Are there implications of reducing urate too much?
Answer from: at Academic Institution
In my opinion, there are no known adverse outcomes related to very low serum urate levels. Suspected, but not proven, associations of dementia with sustained hypouricemia, have been used to create an impression that there may be one benefit of avoiding hypouricemia. There are multiple reasons for no...
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