Is there a role for extended treatment volumes (elective nodal) in the definitive treatment of parameningeal rhabdomyosarcoma in a young adult?

Would the translocation status influence your decision? Are there specific subsites where elective radiotherapy likely offers a higher therapeutic ratio? Would retropharyngeal nodal involvement modify your decision? Is there a role for sentinel lymph node evaluation prior to chemotherapy?

Answer from: Radiation Oncologist at Academic Institution

If by "extended treatment volumes" you are asking about cranial or craniospinal radiation therapy, the answer is an emphatic NO. We demonstrated by careful review of patterns of failure that cranial irradiation was unnecessary in PM-RMS (Michalski 2004). The IRS and subsequently the COG have abandon...

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Radiation Oncologist at St Jude Children's Research Hospital
I agree that extended cranial volumes are unlikely...

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Is there a role for extended treatment volumes (elective nodal) in the definitive treatment of parameningeal rhabdomyosarcoma in a young adult?

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