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Should capecitabine be administered at a specific time prior to RT in pre-op chemoradiation treatment for rectal cancer?
Would taking the drug at a specific time point prior to their radiation appointment time to maximize blood levels of the drug be clinically beneficial?
Answer from: Radiation Oncologist at Academic Institution
We looked at this question and published our analysis in 2007. We looked at the timing of administration and radiation delivery. The dosing of capecitabine was standardized and the radiation timing was random. The 2 year local control, distant control, and disease-free survival were nearly identical...
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