What dose is needed for salvage RT for recurrent endometrial cancer in untreated PA region (who has received pelvic RT) after good PET response to systemic therapy?

For a patient with good response to immunotherapy (unable to receive chemotherapy due to kidney function, comorbidities) where previously avid LN have resolved, what dose is needed for microscopic disease? Is 50.4Gy enough or would you boost the previous involved region to a higher dose 54Gy or more?

Answer from: Radiation Oncologist at Community Practice

I usually treat 45 Gy in 25 fraction to chain, and 55 in 25 to residual normalized node.

Comments

Radiation Oncologist at Tampa Bay Radiation Oncology
Agree with Dr. Beriwal. 45 Gy in 25 fxs with an SI...

Radiation Oncologist at Washington University School of Medicine
Agree with Dr. Beriwal's recommendation. In additi...

Radiation Oncologist at Harold C Simmons Comprehensive Cancer Center/UT Southwestern
Agree, but would tailor boost dose to residual nod...

Radiation Oncologist at CCare
What doses would you use for the boosts?

Radiation Oncologist at Varian Medical Systems/Allegheny health network
55 at 2.2 or 57.5 at 2.3

Radiation Oncologist at CCare
Thanks!

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What dose is needed for salvage RT for recurrent endometrial cancer in untreated PA region (who has received pelvic RT) after good PET response to systemic therapy?

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