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What dose would you give for unresectable anaplastic thyroid carcinoma?
Is there a hypofractionated dose regimen that would be suitable for palliation prior to the patient going to hospice?
Answer from: Radiation Oncologist at Academic Institution
Palliation sometimes can be more complex than definitive treatment in head and neck, particularly when the patient does not have distant disease. Having trained at MDA, I have frequently used the Quad shot (14Gy/4fx, given with BID fx c 6h in between fx) (Corry et al Radiother Oncol, 2005) It is r...
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Answer from: Radiation Oncologist at Academic Institution
I also trained at MDA (a lot later ha ha) and I also like the "quad shot" concept. Except I/we do it the way the GYN/RTOG 85-02 palliation trial did it. 370 cGy BID x 2 days, repeat 3 times. We come off the spinal cord for the third cycle. I've also used 30/10 and 45/15; with IMRT you can keep the s...