What factors affect your decisions in in the initial management of a stage IIIB bladder cancer?

How do you decide between downstaging chemotherapy or upfront concurrent chemoradiotherapy? Both are listed as NCCN options.

Answer from: Medical Oncologist at Academic Institution

For cN+ bladder Ca, I start with induction chemotherapy aiming for 4-6 cycles (restaging initially after 3 cycles and continue to 1-3 more cycles depending on response & tolerance) since the risk of micro-Mets is exceedingly high. If a patient has a great response to induction chemo, options may...

Comments

Radiation Oncologist at Jacob E Locke MD PA
N+ could be a wide range of patients. Is there any...

Medical Oncologist at University of Washington School of Medicine
I think that this would be a very reasonable optio...

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What factors affect your decisions in in the initial management of a stage IIIB bladder cancer?

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