What is the optimal management of a pelvic sidewall recurrence of endometrial cancer in a patient who has not previously received radiation?  

A significant percentage of women with a pelvic sidewall recurrence can be salvaged with definitive chemoradiation. We would typically use IMRT, treating a CTV encompassing the pelvic nodes to 45-50 Gy and using an initial integrated boost to treat the gross disease to 50-55.  A sequential boos...

I agree with @Ann H. Klopp's approach but there are many ways to skin a cat. I agree with @David K. Gaffney that those patients with sidewall recurrences have worse prognosis if they receive conventional doses of external beam radiation therapy. Our approach would be more aggressive for a patie...