What treatment technique do you recommend for maximum hearing preservation when treating a vestibular schwannoma: fractionated radiosurgery (25 Gy in 5 fractions) or single fraction radiosurgery?
One study comparing these techniques (https://www.ncbi.nlm.nih.gov/pubmed/12873685) showed 75% hearing preservation in the single fraction group and 61% in the fractionated group (though not statistically significant).
Answer from: Radiation Oncologist at Academic Institution
HI I was asked to respond to this very interesting question, we have tried both 5Gyx5 and SRS for these cases, and we moved our practice from SRS to hypofractionated a number of years ago. I have been equally disappointed with the outcomes in terms of hearing preservation with both ...