What would you offer postoperatively for a pt with resected 3 separate HPV+ SCC primaries with pN1 disease with ECE who is cisplatin ineligible?

Resected small bilateral tonsil SCC & base of tongue SCC.

The patient received 6 cycles of BEP 30 years ago for testicular cancer, and suffers from ongoing tinnitus and mild/mod peripheral neuropathy.

Answer from: Medical Oncologist at Academic Institution

In view of this patient having ECS and three primaries (including bilateral disease), I would definitely treat postoperatively with chemotherapy in conjunction with radiation therapy. I still favor a platinum-based regimen in view of this patient's neurological toxicity due to previous cisplatin exp...

Comments

Medical Oncologist at Hollywood Private Hospital
Thank you for your thoughtful insights, Dr. @Franc...

Medical Oncologist at University of Michigan Medical School
Our studies were in only HPV+ patients. To date, t...

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What would you offer postoperatively for a pt with resected 3 separate HPV+ SCC primaries with pN1 disease with ECE who is cisplatin ineligible?

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