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When are steroids indicated in the treatment of strep pneumo meningitis?
Does timing relative to initiation of antibiotics matter?
Answer from: at Academic Institution
Yes, I recommend a four-day regimen of dexamethasone 0.4-0.6 mg per kilogram daily given before or with the first dose of antibiotics. Delaying the administration of corticosteroids would reduce the desired anti-inflammatory effects.
van de Beek et al., PMID 14998499
Brouwer et al., PMID&nbs...
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