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When do you consider elective pelvic nodal irradiation for unfavorable intermediate risk prostate cancer?
Do you use decipher, or other genetic testing to determine whether you will include pelvic lymph nodes when you give definitive EBRT? Can you comment on using decipher to determine whether to give ADT and the length of ADT?
Answer from: Radiation Oncologist at Community Practice
I agree with @Mitchell S. Anscher's response. High-volume GG3 often will lead me to consider adding pelvic RT. I think the MSKCC pre-RP nomogram is also helpful- as it will give you an estimate of LN involvement. What is the “right” cut-off for adding pelvic RT, if the risk is >15%? &...
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Radiation Oncologist at Staten Island Radiation Oncology
I agree.
I agree.
Answer from: Radiation Oncologist at Academic Institution
When the risk is 10% or higher based on the MSK and/or Briganti nomograms.
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Radiation Oncologist at Jacob E Locke MD PA
The added morbidity of treating pelvic nodes with ...
The added morbidity of treating pelvic nodes with ...
Answer from: Radiation Oncologist at Academic Institution
I am not aware of data suggesting Decipher predicts for lymph node involvement. Worse outcome, yes. LN involvement specifically, no.GU-010 is evaluating whether Decipher can be used as a predictive marker as to the benefits of ADT, but until results are published, I would not use it as a predictive ...
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Radiation Oncologist at University of Florida
I’m risk averse. 10% or higher, I’d tr...
I’m risk averse. 10% or higher, I’d tr...
Thank you for the recommendations. One of the radi...
There is a good data that Decipher predicts for pe...