When is SBRT or hypofractionated radiation appropriate as adjuvant treatment for pancreatic cancer?
What are the targets (tumor bed, positive margin, nodes etc.)?
Answer from: Radiation Oncologist at Academic Institution
There may be a variety of opinions about this question. 33 Gy in 5 looks to be as least as good as 50.4 Gy in 28 in unresectable pancreatic cancer and has had some improved pathologic responses in borderline resectable pancreatic cancer in experienced hands (Hermann et al., PMID 25538019). However, ...
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Medical Oncologist at Siri Onclogy and hematology Infusion Service Please, could we have the reference to 5-year dise...
Answer from: Radiation Oncologist at Community Practice
As @Christopher H. Crane outlines above, the management of resected pancreatic cancer is controversial and a “standard” adjuvant treatment approach has yet to be determined. We patiently await the results of RTOG 0848, the current cooperative group trial evaluating the role of conve...
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Radiation Oncologist at Washington University School of Medicine To make sure I understand the target volumes corre...
Radiation Oncologist at HistoSonics, Inc. In response to your questions:
Yes, the afferen...
Medical Oncologist at Siri Onclogy and hematology Infusion Service Most would accept that FOLFIRINOX or modified FOLF...
Answer from: Radiation Oncologist at Community Practice
Hypo will result in damage to surrounding tissues/organs if the patient lives >1 year. If the expected survival is 1 year or less (as is typical for pancreatic ca), then hypofractionated RT is fine.
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Radiation Oncologist at Memorial Sloan-Kettering Cancer Center Based on what data?
Radiation Oncologist at St. Barnabas Medical Center In a patient who received neoadjuvant chemo follow...
Please, could we have the reference to 5-year dise...