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Topics:
Hematologic Malignancies • Pediatric Hematology/Oncology • Medical Oncology • Bone Marrow Transplant • Internal Medicine • Hematology
With new data showing similar outcomes of mismatched unrelated donor and haploidentical related donor allogeneic transplants using post transplant cyclophosphamide, how does one decide which donor is optimal?
If given both options, which donor would one prefer: haploidentical related donor or 7/8 mismatched unrelated donor using post transplant cyclophosphamide?
Answer from: Medical Oncologist at Academic Institution
It is certainly an unresolved question, and the short answer is that either would be an acceptable option with post-transplant cyclophosphamide (and I have used both). All recipients of mismatched donor transplants should be tested for the presence of donor specific antibodies, and their presence co...
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