Would you give adjuvant chemotherapy to a distal esophageal adenocarcinoma T3NxM0 who s/p chemo-radiation and esophagectomy, had a complete pathologic response (ypT0N0)?  

For patients with esophageal adenocarcinoma who receive neoadjuvant chemoradiation, there are no data to support the use of adjuvant chemotherapy, irrespective of the pathologic response. However, if the patient does not have a pathologic complete response, adjuvant nivolumab is indicated according ...