Would you offer breast conservation or PMRT (if clinically warranted) to someone with breast cancer in the context of Li Fraumeni syndrome?

Answer from: Radiation Oncologist at Community Practice

I would be very reluctant as the benefit has to be weighed against the high risk of a second cancer that has been reported in limited published literature .

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Would you offer breast conservation or PMRT (if clinically warranted) to someone with breast cancer in the context of Li Fraumeni syndrome?

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