Would you recommend adjuvant chemoradiation for T1N0 gastric adenocarcinoma status post R0 resection but no D2 lymph node dissection?
Does the lack of D2 dissection automatically necessitate adjuvant chemoradiation therapy (ie <5 LN obtained)? Would the presence of high risk factors influence the recommendation (high grade, +LVSI, +PNI)?
Answer from: Radiation Oncologist at Community Practice
I would not recommend adjuvant chemoradiation for a patient with an R0 resection for a T1N0 gastric adenocarcinoma even though a D2 dissection was not performed. If the patient had high risk factors, adjuvant chemotherapy may be appropriate in view of distant metastasis rates of ~ 30% with T1-2N0 le...