Questions discussed in this category
NCCN states that per an AS paradigm for low risk and FIR prostate cancer, a PSA should not be collected any more than every 6 months, with DRE, mpMRI ...
Do you insist on ambulatory/home blood pressures to rule in/out white coat hypertension? Does your practice have a system to log patients' BPs to supp...
If so, for how long afterwards do you think the patient needs to continue the exercises?
Patients in their later 40s with favorable intermediate-risk prostate cancer s/p 7000cGy/28 EBRT only.
If so, when do you resume?
The serum testosterone is minimally low at 250 and the patient has some fatigue.
Assume a life expectancy of approximately 5-10 years. What factors would influence your consideration of intermittent ADT vs. watchful waiting?
How soon is too soon after surgery to check PSA?
Is there any available therapy?
What do you tell men who want to know if their testosterone has recovered?
Some patients will go on to develop asymptomatic intermittent hematuria which can persist... In patients with scant hematuria, what's your routine car...
If this upstages the patient, do you modify treatment recommendations?
This applies to both de novo cases and patients who have previously received injectable agents.
What concerns do you have about a colonoscopy?
Indefinitely seems to be a typical recommendation, but rarely done.
In particular, for men who have no strong indication for ADT?
In a patient who has a rising PSA, palpable nodule, MRI findings etc., is it ethical to treat the patient with inadequate information and ri...
In patients with new bone pain and without any evidence of bone metastases receiving GnRH agonists, how do you manage pain symptoms?
NCCN guidelines offer suggested schedules for interval imaging and laboratory studies, but also make it clear that the quality of evidence for these r...
Two retrospective studies from Stanford showed that patients who received ADT had an increased risk of dementia and Alzheimer's. Is this finding ...
How might a recent (within 6 months) myocardial infarction affect your recommendations?
Are there specific subsets for whom these results should change management?
With ultra-sensitive PSA, it's unclear to me whether a doubling from 0.01 to 0.02 or 0.02 to 0.04 is significant. Is there a certain value that you wo...
More specifically, which cardiac risk factors do you look for? Diabetes? Previous MI? Dyslipidemia? Peripheral vascular disease? CHF?
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Papers discussed in this category
European urology, 2013-12
CA Cancer J Clin, 2010 May-Jun
J Natl Cancer Inst, 2010 Jan 6
BJU international, 2014-12
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-06-20
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-02-20
JAMA oncology, 2016-04
JAMA oncology, 2017-01-01
JAMA, 2009-08-26
European urology, 2015-05
JAMA, 2008-01-23
The Lancet. Oncology, 2007-01
Radiother Oncol, 2015 Dec 15
Int J Urol, 2015 Jul 14
Int J Radiat Oncol Biol Phys,
J Sex Med, 2013 Feb 22
Cancer,
Urol Int,
Lancet Oncol, 2017 Jul 28
International journal of radiation oncology, biology, physics, 2010-06-01
International journal of radiation oncology, biology, physics, 2012-01-01
Adv Urol, 2011 Oct 16
Eur Urol, 2009 Dec 18
Scandinavian journal of urology and nephrology, 2004
BJU international, 2005-10
Andrologia, 2017-02
Current opinion in urology, 2007 Nov
N Engl J Med, 2021 Jun 23