Questions discussed in this category
Do you insist on ambulatory/home blood pressures to rule in/out white coat hypertension? Does your practice have a system to log patients' BPs to supp...
Is there a specific tyrosine kinase inhibitor that you would prefer to use?
For radiation oncologists, how do you ameliorate the risk for radiation-related injury to epicardial coronaries during treatment sessions?
If so, how long are they on degarelix before the switch?
(i.e. frequency of serial BNP, troponin, cMRI)
How do you use this information in clinical practice?
E.g. in a patient with tenuous cardiac function, would starting treatment several weeks earlier potentially improve outcomes?
Would you continue ibrutinib even if they are placed on anti-platelet therapy such as clopidogrel or ticagrelor?
When do you switch to an altern...
Do you feel comfortable with BTK inhibitors in these patients?
In ELEVATE-RR patients on a/c were excluded, and rate of atrial fibrillation in the ac...
If no anthracycline, what alternative regimen would you consider?
Is there any safety data to proceed with TKIs/TDM-1 or to proceed as standard with THP?
Do you repeat the loading dose of trastuzumab?
Would you even consider trabectedin in this case given its cardiotoxicity?
Patient does not want chemo but is tolerating these well otherwise.
When 5FU is a backbone to so many regimens, when (if ever) do you consider re-challenging so as not to abandon an entire line of therapy?
Can these patients be re-challenged with Herceptin?
How does it vary for patients with a history of hypertension, diabetes, CHF, and coronary artery disease?
How might a recent (within 6 months) myocardial infarction affect your recommendations?
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Papers discussed in this category
JAMA, 2009-08-26
European urology, 2015-05
JAMA, 2008-01-23
JAMA oncology, 2016-04
The New England journal of medicine, 2015-12-17
Blood, 2022 Jul 14
Leukemia, 2021 Apr 27
J Am Coll Cardiol, 2019 Oct 01
Cochrane Database Syst Rev, 2008 Apr 16
Eur. J. Cancer, 2013 May 22
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-09-01
Breast cancer research and treatment, 2019-05
Clin Colorectal Cancer, 2018 Oct 10
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997-06
The New England journal of medicine, 2014-11-13
Lancet Oncol., 2017 Sep 11
The Lancet. Oncology, 2017-08
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-03-10
Clinical cancer research : an official journal of the American Association for Cancer Research, 2018-12-01
Annals of Oncology, 2021 Sep 29
J Urol, 2019 Jun 12
Eur J Heart Fail, 2020 Aug 06
Eur Heart J Cardiovasc Imaging, 2022 Sep 10
Eur Heart J, 2022 Nov 01
JACC CardioOncol, 2022 Dec 20
The American journal of cardiology, 2018-12-01
Curr Oncol, 2021 Oct 13
Cardiooncology, 2019 Jan 29
Haematologica, 2010-07
The American journal of medicine, 1997-01
Haematologica, 2019 Aug 14
Pediatr Transplant, 2021 Aug
Br J Haematol, 2023 May 2
Bone marrow transplantation, 2022 Dec 27
Eur Heart J, 2022 Jan 31
J Thorac Cardiovasc Surg, 2021 May 08
JACC CardioOncol, 2021 Sep 21
J Am Heart Assoc, 2020 Jan 21
Circulation, 2020 Jun 15
Journal of the American Heart Association, 2021 Sep 06