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Endocrinology
Pituitary Disorders
Questions discussed in this category
When do you consider using setmelanotide for treatment of hypothalamic obesity?
1 Answer available
Do you have any specific recommendations to prevent large fluctuations in sodium levels during a colonoscopy prep in patients with central diabetes insipidus on DDAVP?
2 Answers available
Should dopamine agonist treatment stop in pregnant patients with recurrent prolactinoma despite prior surgery?
1 Answer available
What specific clinical factors would drive you to recommend surgical intervention for patients with small, nonfunctional pituitary adenomas who exhibit no neurological symptoms?
1 Answer available
When and how do you taper off cabergoline therapy for treatment of microprolactinoma?
1 Answer available
What is your approach to managing patients with new laboratory evidence of hypopituitarism (e.g. very low plasma ACTH level and low morning serum cortisol) and a remote history of trans-sphenoidal surgery for NFPA?
1 Answer available
Does growth hormone (GH) replacement therapy reduce the risk of fractures in patients with GH deficiency?
1 Answer available
Is Macrilen (macimorelin Dx) still available in the US for diagnosis of adult growth hormone deficiency (AGHD)?
1 Answer available
Should patients with non-functional pituitary macroadenomas with persistent, but tolerable, headaches be recommended for surgery?
1 Answer available
Given the new 2022 WHO classification of pituitary tumors, should we be regularly counseling our patients about the risk of malignancy for what we previously referred to as pituitary adenomas but now classified as pituitary neuroendocrine tumors (PitNETs)?
Asa et al., PMID 35291028
1 Answer available
What is your approach to differentiating diabetes insipidus from primary polydipsia in the outpatient setting?
1 Answer available
Does preoperative use of somatostatin receptor ligand improve remission rates after surgery for acromegaly?
1 Answer available
When do you check macroprolactin in the evaluation of hyperprolactinemia?
2 Answers available
Does norethindrone suppress FSH, LH completely?
If not, what can be possible causes for a postmenopausal woman to have FSH, LH < 0.3 with low E2, and being asymptomatic and doing well otherwise? ...
2 Answers available
Do patients with an elevated IGF-1 level and features of acromegaly need to have confirmatory growth hormone suppression testing with OGTT?
Can a diagnosis of acromegaly be made with just an elevated IGF-1 level in patients with features of acromegaly?
2 Answers available
Should oral combined contraceptives be held prior to overnight dexamethasone suppression test to rule out Cushings?
If so, how long should OCPs be held to reliably trust the dex suppression test results?
2 Answers available
Can combined oral contraceptive use cause falsely elevated 24-hour urine-free cortisol?
2 Answers available
What is your protocol to starting/stopping glucocorticoid replacement in Cushing disease patients after their transsphenoidal resection surgery?
1 Answer available
How often would you repeat testing in a patient suspected of Cyclic Cushing's?
And is there a preferred diagnostic test? Whenever cyclic hypercortisolemia is suspected, it is advised that evaluation should be repeated for months,...
2 Answers available
For a TSH producing microadenoma, would you recommend surgery vs methimazole if the patient is elderly and the tumor is relatively small?
The female patient is in her late 70s with cardiac disease (likely due to chronic hyperthyroidism that was missed due to non-suppressed TSH). I’...
1 Answer available
Should patients with asymptomatic GH deficiency be treated with GH replacement therapy if they have prior known severe CAD?
1 Answer available
Does caution have to be used in GH replacement therapy in any and all types of cancer history?
1 Answer available
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Papers discussed in this category
The lancet. Diabetes & endocrinology, 2021 Oct 20
Consensus on diagnosis and management of Cushing's disease: a guideline update.
Pituitary, 2022 May 26
The NETting of pituitary adenoma: a gland illusion.
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